Dr. Abby Collier

Dr. Abby C. Collier

Assistant Professor of Pharmacology
John A. Burns School of Medicine
University of Hawai’i at Manoa

B.Sc. University of Auckland 1998
Ph.D. University of Auckland Medical School 2002

 

Announcements

  • We are proud and happy to receive a grant from the NIH/NCRR Centers for Biomedical Research Excellence.

 

Overview

Our lab studies the metabolism and pharmacokinetics of endobiotics and xenobiotics (especially drugs) with particular emphasis on Phase II conjugative enzymes. Ongoing projects include:

  • The development of hepatic metabolizing enzymes in children and its impact on adverse drug reactions, childhood development and maturation.
  • The contribution of metabolizing enzymes in the fetus, placenta and maternal liver to pregnancy and fetal development.
  • Metabolizing enzyme inhibition and its role in endocrine disruption, cancer, chronic disease and complications of pregnancy (birth defects).
  • The effects of infection, inflammation and disease on drug metabolism in humans.